BC Mental Health and Addictions Research Institute

Publications - Alasdair Barr

2006/07 to 2010/11

Smith, G.N., MacEwan, G.W., Kopala, Lang, D.J., Barr, A.M., Honer, W.G., Ehmann, T.S., Good, K., Thornton, A.E., & Neilson, H. (2010) Prenatal tobacco exposure in first-episode psychosis. Schizophrenia Research, 119(1-3), 271272.

Procyshyn, R. M., Honer, W. G., Wu, T. K., Ko, R. W., McIsaac, S. A., Young, A. H., Johnson, J.L., & Barr, A. M. (2010). Persistent antipsychotic polypharmacy and excessive dosing in the community psychiatric treatment setting: A review of medication profiles in 435 canadian outpatients. The Journal of Clinical Psychiatry, 71(5), 566-573.

Procyshyn, R. M., Barr, A. M., Flynn, S., Schenk, C., Ganesan, S., & Honer, W. G. (2010). Long-acting injectable risperidone in treatment refractory patients: A 14-week open- label pilot study. Schizophrenia Research, 123(2-3), 273-275.

Procyshyn, R. M., Barr, A. M., Brickell, T., & Honer, W. G. (2010). Medication errors in psychiatry: A comprehensive review. CNS Drugs, 24(7), 595-609.

Okoli, C. T., Khara, M., Procyshyn, R. M., Johnson, J. L., Barr, A. M., & Greaves, L. (2010). Smoking cessation interventions among individuals in methadone maintenance: A brief review. Journal of Substance Abuse Treatment, 38(2), 191- 199.

Boyda, H. N., Tse, L., Procyshyn, R. M., Honer, W. G., & Barr, A. M. (2010). Preclinical models of antipsychotic drug-induced metabolic side effects. Trends in Pharmacological Sciences, 31(10), 484-497.

Barr, A. M., Honer, W. G., Johnson, J. L., Wu, T. K., & Procyshyn, R. M. (2010). A comparison of antipsychotic drug-defined daily doses versus chlorpromazine equivalent doses in patients with or without extrapyramidal motor symptoms. Journal of Clinical Psychopharmacology, 30(6), 741-743.

Barakauskas, V. E., Ypsilanti, A. R., Barr, A. M., Innis, S. M., Honer, W. G., & Beasley, C. L. (2010). Effects of sub-chronic clozapine and haloperidol administration on brain lipid levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34(4), 669-673.

Barakauskas, V. E., Beasley, C. L., Barr, A. M., Ypsilanti, A. R., Li, H. Y., Thornton, A. E., Wong, H., Rosokija, G., Mann, J.J., Mancevski, B., Jakovski, Z., Davceva, N., Illevski, B., Dwork, A.J., Falkai, P., & Honer, W. G. (2010). A novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 35(5), 1226-1238.

Barr, A.M., Boyda, H.N., & Procyshyn, R.M. (2010). Methamphetamine abuse. Withdrawal & Tolerance. Olmstead, C. (Eds). Animal Models of Drug Addiction. Totawa, NJ: Humana Press.

Procyshyn, R.M., & Barr, A.M. Insomnia. In: Repchinsky C, editor. Patient Self-Care: Helping patients make therapeutic choices, 2nd Edition. Ottawa: Canadian Pharmacists Association: 2010, Ottawa, Canada

Lecomte, T., Mueser, K.T., MacEwan, G.W., Laferriere-Simard, M.C., Thornton, A.E., Buchanan, T., Goldner, E., Brink, J., Ehmann, T.S., Lang, D., Kang, S., Barr, A.M., & Honer, W.G. (2010). Profiles of individuals seeking psychiatric help for psychotic symptoms linked to methamphetamine abuse Baseline results from the MAPS (methamphetamine and psychosis study) Mental Health Subst Abuse, 3, 168-181.

Smith, G.N., Wong, H., MacEwan, G.W., Kopala, L.C., Ehmann, T.S., Thornton, A.E., Lang, D.J., Barr, A.M., Procyshyn, R., Austin, J.C., Flynn, S.W., & Honer, W.G. (2009). Predictors of starting to smoke cigarettes in patients with first-episode psychosis. Schizophrenia Research, 108(1- 3), 258-264.

Rosland, M., Szeto, P., Procyshyn, R., Barr, A.M., & Wasan, K.M. (2007). Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography. Drug development and industrial pharmacy, 33(10), 1158-1166.

Procyshyn, R. M., Honer, W. G., & Barr, A. M. (2009). Do serum lipids predict response to clozapine treatment? Journal of Psychiatry & Neuroscience : JPN, 34(2), 168.

Kinney, J.W., Sanchez-Alavez, M., Barr, A.M., Criado, J.R., Crawley, J.N., Behrens, M.M., Henriksen, S.J., & Bartfai, T. (2009). Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation. Neurobiology of learning and memory, 92(3), 429- 438.

Honer, W. G., Procyshyn, R. M., Chen, E. Y., MacEwan, G. W., & Barr, A. M. (2009). A translational research approach to poor treatment response in patients with schizophrenia: Clozapine-antipsychotic polypharmacy. Journal of Psychiatry & Neuroscience : JPN, 34(6), 433-442.

Green, A.D., Barr, A.M., & Galea, L.A. (2009). Role of estradiol withdrawal in 'anhedonic' sucrose consumption: a model of postpartum depression. Physiology & behavior, 97(2), 259- 265.

Burns, K.D., Jenkins, W., Yeh, D., Procyshyn, R.M., Schwartz, S.K.W., Honer, W.G., & Barr, A.M. (2009). Delirium after cardiac surgery: a retrospective review of incidence and risk factors in a Canadian sample - a case-control study. BC Medical Journal, 51, 206-210.

Barr, A. M., Procyshyn, R. M., Hui, P., Johnson, J. L., & Honer, W. G. (2008). Self-reported motivation to smoke in schizophrenia is related to antipsychotic drug treatment. Schizophrenia Research, 100(1-3), 252-260

Barr, A. M., Fish, K. N., Markou, A., & Honer, W. G. (2008). Heterozygous reeler mice exhibit alterations in sensorimotor gating but not presynaptic proteins. The European Journal of Neuroscience, 27(10), 2568-2574.

Procyshyn, R. M., Wasan, K. M., Thornton, A. E., Barr, A. M., Chen, E. Y., Pomarol-Clotet, E., Stip, E., Williams, R., MacEwan, G.W, Birmingham, C.L., & The Clozapine and Risperidone Enhancement Study Group. (2007). Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. Journal of Psychiatry & Neuroscience : JPN, 32(5), 331-338.

Panenka, W. J., Khorram, B., Barr, A. M., Smith, G. N., Lang, D. J., Kopala, L. C., Vandorpe, R.A., & Honer, W. G. (2007). A longitudinal study on the effects of typical versus atypical antipsychotic drugs on hippocampal volume in schizophrenia. Schizophrenia Research, 94(1-3), 288-292.

Honer, W. G., Thornton, A. E., Sherwood, M., MacEwan, G. W., Ehmann, T. S., Williams, R., Kopala, L.C., & Barr, A. M. (2007). Conceptual and methodological issues in the design of clinical trials of antipsychotics for the treatment of schizophrenia. CNS Drugs, 21(9), 699- 714.

Hill, M.N., Barr, A.M., Ho, W.S., Carrier, E. J., Gorzalka, B.B., & Hillard, C.J. (2007). Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. Journal of neurochemistry, 103(1), 47-56.

Conti, B., Maier, R., Barr, A.M., Morale, M.C., Lu, X., Sanna, P.P., Bilbe, G., Hoyer, D., & Bartfai, T. (2007). Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine. Molecular psychiatry, 12(2), 167-189.

Barr, A.M., MacLaurin, S.A., Semenova, S., Fish, K.N., & Markou, A. (2007). Altered performance of reelin-receptor ApoER2 deficient mice on spatial tasks using the Barnes maze. Behavioral neuroscience, 121(5), 1101- 1105.

Barr, A.M., Fish, K.N., & Markou, A. (2007). The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice. Neuropharmacology, 52(4), 1114-1123.

Barr, A. M., Young, C. E., Phillips, A. G., & Honer, W. G. (2006). Selective effects of typical antipsychotic drugs on SNAP-25 and synaptophysin in the hippocampal trisynaptic pathway. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 9(4), 457-463.

Barr, A.M., Powell, S.B., Markou, A., & Geyer, M.A., (2006). Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology; 51(3): 457-465.

Barr, A.M., Panenka, W.J., MacEwan, G.W., Thornton, A.E., Lang, D.J., Honer, W.G., & Lecomte, T. (2006). The need for speed: an update on methamphetamine addiction. Journal of psychiatry & neuroscience : JPN, 31(5), 301-31.

Barr, A.M., Kinney, J.W., Hill, M.N., Lu, X., Biros, S., Rebek, J. Jr., & Bartfai, T. (2006). A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests. Neuroscience letters, 405(1-2), 111-115.

Barr, A.M., Sawada, K., Young, C.E., & Honer, W.G. (2006). Relevance of presynaptic proteins to neuropsychiatric disorders. In: Eds A. Dityatev and A. El-Husseini, Molecular mechanisms of synaptogenesis. Berlin: Springer Press.